The Ebyte E22-400T33S is a wireless serial port module (UART) based on SEMTECH's SX1268, working at 410.125 ~ 493.125MHz (default 433.125MHz),TTL level output, compatible with 3.3V and 5V IO port voltage. Compared with the traditional SX1278 solution, it has a longer transmission distance, faster speed, lower power consumption, and smaller size; it supports functions such as air wake-up, wireless configuration, carrier monitoring, automatic relay. communication keys and sub-package length setting. Ebyte provides customized development services on it. An obvious advantage is that SX1268 covers wider frequency range.
Brand Name:EBYTE
Origin:Mainland China
Condition:New
Type:Drive IC
Model Number:E22-400T33S-V2.1
Operating Temperature:-40-85℃
Package:SMD
| Main parameter | Min. | Typ. | Max. | Unit | Remark |
|---|---|---|---|---|---|
| Operating voltage | 3.3 | 5.0 | 5.5 | V | ≥5.0 V ensures output power |
| Communication level | - | 3.3 | - | V | For 5V TTL, It is recommended to add level conversion |
| TX current | - | 1000 | - | mA | Instant power consumption |
| RX current | - | 13 | - | mA | - |
| Sleep current | - | 2 | - | μA | Software is shut down |
| Operating temperature | -40 | - | +85 | ℃ | - |
| Operating parameter | Performance | Remark |
|---|---|---|
| Operating frequency | 410.125~493.125MHz | Support ISM band |
| Tx power | 33 dBm | - |
| Receiving sensitivity | -128dbm | Air data rate is 2.4kbps |
| Air data rate | 2.4k~62.5kbps | Controlled via user’s programming |
| Distance for reference | 1600m | Test condition:clear and open area, antenna gain: 5dBi,antenna height: 2.5m,air data rate: 2.4kbps |
| Size | 25*40.5 mm | - |
| Antenna | IPEX/stamp hole | 50 ohm impedance |
| Communication interface | UART | - |
| Package | SMD | - |




Practical Application Scenarios
1. Smart Agriculture Field Data Monitoring
In large-scale smart farming, the E22-400T33S provides reliable connectivity for soil moisture, pH level, and temperature sensors spread across hectares of land. Its LoRa modulation technology ensures stable transmission even in environments with dense vegetation and hilly terrain, allowing farmers to aggregate data from distributed endpoints into a single central gateway via long-range wireless links.
2. Urban Utility Meter Reading (AMR/AMI)
Utility companies utilize this module for automated water and electricity meter reading. Its high penetration capabilities allow the signal to pass through underground meter pits and concrete building structures. With the support for automatic relay, the module can extend the coverage of the metering network without requiring complex cabling infrastructure.
3. Industrial Asset Tracking and Safety
The module serves as an ideal communication backbone for industrial safety equipment, such as perimeter intrusion sensors and worker safety beacons. The “air wake-up” feature allows battery-powered sensors to remain in deep-sleep mode, drastically reducing power consumption and extending the operational lifespan of the equipment in harsh, remote industrial environments.
FAQ Section
1. How does the SX1268 chipset improve performance over the older SX1278?
The SX1268 chipset provides significant improvements in power efficiency, a broader frequency coverage range, and higher sensitivity. These enhancements result in a more robust link budget, allowing for longer communication distances and better performance in environments with high electromagnetic interference compared to the legacy SX1278-based solutions.
2. Is additional level-shifting hardware required for 5V PLCs?
No, the module is engineered with native support for both 3.3V and 5V IO voltage levels. This hardware-level compatibility allows you to connect the E22-400T33S directly to 5V microcontrollers or industrial PLC serial ports without the need for external voltage level shifters or pull-up resistors.
3. Can I update the module configuration without accessing the physical hardware?
Yes, the module supports “wireless configuration” via the air interface. This allows engineers to modify parameters like transmission power, spreading factor, and bandwidth remotely without needing to physically connect a computer or programmer to the module, which is critical for maintaining installed devices in inaccessible or hazardous locations.