The Ebyte E22 series is an ultra-compact (10*10mm) industrial-grade SMD LoRa wireless transceiver module built on Semtech SX1268 / SX1262 with an integrated high-precision TCXO crystal oscillator, delivering up to 22dBm (160mW) transmit power and 6km line-of-sight range over standard SPI interface, featuring ultra-low sleep current (0.16uA), fast air data rates up to 62.5kbps, and wide industrial temperature tolerance (-40°C to +85°C) for space-constrained smart metering, medical telemetry, and IoT sensor nodes.
Key Features & Advantages
- Ultra-Miniature 10*10mm SMD Form Factor with Built-in TCXO: Engineered with a high-precision 32MHz temperature-compensated crystal oscillator (TCXO), maintaining stable frequency accuracy across severe industrial temperature fluctuations (-40°C to +85°C) in extreme environments.
- Semtech SX1262/SX1268 Core with Extended 6km Communication Range: Leverages next-generation LoRa modulation to achieve superior anti-interference performance and deep signal penetration, outperforming traditional FSK/GFSK radio modules.
- Ultra-Low Power Consumption with 0.16uA Deep Sleep Current: Features software shutdown deep sleep current as low as 0.16uA and 7mA receiving current, substantially extending battery life in compact remote IoT nodes.
- High-Speed SPI Bus with Programmable Air Data Rates (0.018 ~ 62.5 kbps): 1.27mm stamp-hole SMD interface directly exposes SPI data registers, multi-level power settings, and 256-byte FIFO buffers for fast integration with host microcontrollers (STM32, ESP32, nRF52).
Core Specifications
| Parameter | Specification / Value |
|---|---|
| RF Transceiver IC | Semtech SX1268 (400MM22S) / Semtech SX1262 (900MM22S) |
| Operating Frequencies | 410 ~ 493 MHz (400MM22S) / 850 ~ 930 MHz (900MM22S) |
| Max Transmit Power | 22 dBm (approx. 160 mW, multi-level adjustable) |
| Communication Distance | Up to 6 km (Line-of-Sight, clear outdoor environment) |
| Oscillator Type | 32MHz High-Precision Active TCXO (Temperature Compensated) |
| Host Interface | Standard SPI (SCK, MISO, MOSI, NSS, BUSY, DIO1, DIO2, DIO3) |
| Air Data Rate | 0.018 ~ 62.5 kbps (programmable) |
| Supply Voltage & Current | DC 1.8V ~ 3.7V (TX: 100~140mA @22dBm, RX: ~7mA, Sleep: ~0.16uA) |
| Antenna Connection | 1.27mm Stamp Hole (50 Ohm characteristic impedance) |
| Operating Temperature | -40 to +85 deg C (Industrial Grade) |
| Dimensions & Weight | 10 * 10 * 2.5 mm, 0.5 +/- 0.1 g |
Product Selection Guide
Notice for Selection: Please select between 433MHz/470MHz (Asia/Europe) and 868MHz/915MHz (Europe/Americas) frequency bands according to your regional ISM regulations, and choose between standalone modules or pre-matched antenna packages.
| Model SKU | Frequency Band | RF Chipset | Tx Power | Package / Included Antenna | Host Interface | Dimensions |
|---|---|---|---|---|---|---|
| E22-400MM22S(T) | 410 ~ 493 MHz | Semtech SX1268 (TCXO) | 22 dBm (160mW) | Standalone SMD Module | SPI | 10 * 10 mm |
| E22-400MM22S(T) + TX433-FPC-3208 | 410 ~ 493 MHz | Semtech SX1268 (TCXO) | 22 dBm (160mW) | Module + FPC Flexible Antenna | SPI | 10 * 10 mm |
| E22-400MM22S(T) + TX433-JKS-IPX20 | 410 ~ 493 MHz | Semtech SX1268 (TCXO) | 22 dBm (160mW) | Module + Rubber Duck Antenna Kit | SPI | 10 * 10 mm |
| E22-900MM22S(T) | 850 ~ 930 MHz | Semtech SX1262 (TCXO) | 22 dBm (160mW) | Standalone SMD Module | SPI | 10 * 10 mm |
| E22-900MM22S(T) + TX915-FPC-4510 | 850 ~ 930 MHz | Semtech SX1262 (TCXO) | 22 dBm (160mW) | Module + FPC Flexible Antenna | SPI | 10 * 10 mm |
| E22-900MM22S(T) + TX915-JKS-IPX20 | 850 ~ 930 MHz | Semtech SX1262 (TCXO) | 22 dBm (160mW) | Module + Rubber Duck Antenna Kit | SPI | 10 * 10 mm |














Industrial Installation & Wiring
The E22-400MM22S(T) and E22-900MM22S(T) modules feature a compact 20-pin 1.27mm pitch stamp-hole SMD package (10 * 10 * 2.5 mm), engineered for automated SMT pick-and-place manufacturing. SPI interface lines (SCK, MOSI, MISO, NSS, BUSY, DIO1, DIO2, DIO3) connect directly to standard 3.3V GPIOs on host MCUs (STM32, ESP32, Raspberry Pi RP2040). Power supply requires 1.8V to 3.7V DC (recommended 3.3V with ceramic decoupling capacitors placed close to VCC/GND pins). RF pin 6 (ANT) requires a 50 Ohm matched microstrip line leading to the antenna connector.


Practical Application Scenarios
1. Wireless Automated Meter Reading (AMR) in Dense Urban Buildings
Water, gas, and heat meters located inside underground utility basements and reinforced concrete shafts suffer severe signal attenuation. With Semtech LoRa modulation and high sensitivity, the E22-400MM22S(T) / E22-900MM22S(T) delivers reliable 6km penetration, enabling wireless meter nodes to transmit consumption telemetry directly to outdoor concentrators while running for 10+ years on lithium batteries.
2. Smart Medical Devices & Wearable Health Monitoring
Portable medical patient monitors and hospital asset tracking tags require ultra-miniature hardware profiles and strict battery efficiency. Measuring only 10*10mm with 0.16uA deep sleep current, the E22 module fits into compact wearable medical enclosures, transmitting real-time biometrics across hospital wards without adding bulk.
3. Smart Agriculture Greenhouse & Orchard Micro-Climate Telemetry
Agricultural environmental sensors (soil moisture, leaf wetness, solar radiation) are deployed across large outdoor crop zones with fluctuating day-to-night temperatures. The onboard industrial TCXO crystal prevents frequency drift across -40°C to +85°C, ensuring rock-solid wireless link quality throughout winter frosts and summer heatwaves.
4. Industrial Pipeline Pressure & Flow Sensor Telemetry
Chemical processing plants and gas pipelines require battery-powered explosion-proof wireless transmitters for continuous pressure and flow monitoring. Embedded via standard SPI into low-power MCUs, the E22 module periodically wakes up, samples sensor ADCs, and transmits encrypted packets over long distances with minimal power consumption.
FAQ Section
1. What is the benefit of the TCXO (Temperature Compensated Crystal Oscillator) in the "(T)" version?
Standard crystal oscillators experience frequency drift when ambient temperatures shift significantly, degrading RF link quality and reducing range. The integrated high-precision 32MHz TCXO guarantees frequency stability within +/-1.5ppm across the full industrial temperature range (-40°C to +85°C), making it essential for narrowband LoRa communication and harsh outdoor deployments.
2. What is the difference between this SPI module (E22-M) and UART modules (E22-T / E22P-T)?
The E22-400MM22S(T) / E22-900MM22S(T) is a direct SPI radio module, exposing raw Semtech SX1268/SX1262 hardware registers to the host MCU. This allows embedded developers full software control over LoRa modulation parameters, bandwidth, spreading factor (SF5-SF12), coding rates, and custom packet framing. UART modules, in contrast, feature an onboard MCU providing transparent serial transmission.
3. How do I achieve the ultra-low 0.16uA deep sleep current in my firmware?
To enter deep sleep mode, send the SetSleep() command over the SPI bus while setting the warm-start retention bits as desired. Ensure all connected MCU GPIO pins (NSS, MOSI, SCK, DIO) are pulled to inactive logic levels to prevent parasitic current leakage through internal ESD protection diodes.
4. What antenna matching should be designed on the carrier PCB?
Pin 6 (ANT) is matched to 50 Ohms. We recommend laying out a standard 50 Ohm coplanar waveguide or microstrip trace with a pi-matching network (two shunt capacitors and one series inductor/resistor) leading to an IPEX receptacle or SMA connector for fine-tuning impedance in custom enclosures.