The E22-400MM22S is a high-performance, industrial-grade LoRa wireless module based on the new generation Semtech SX1268 RF chip. Featuring an ultra-small 10x10mm SMD package, it delivers a transmission distance of up to 7km with exceptional anti-interference capabilities. Designed for space-constrained IoT applications, this professional-grade module supports multiple modulation methods including LoRa and FSK, ensuring reliable data communication for smart homes and industrial monitoring.
Next-Gen LoRa Modulation
Advanced SX1268/SX1262 solution for longer range and superior interference immunity.
Ultra-Small SMD Volume
10*10*2.5mm compact footprint, ideal for portable and wearable IoT devices.
Ultra-Low Power
Sleep current as low as 180nA, significantly extending battery life for end-nodes.
Industrial-Grade Reliability
Supports -40℃ to +85℃ operating range with high-precision 32MHz industrial crystal.
Technical Specifications
| RF Chip | Semtech SX1268 / SX1262 (Industrial-grade) |
|---|---|
| Operating Frequency | 410~493MHz (400 Series) / 850~930MHz (900 Series) |
| Transmission Power | 22dBm (approx. 160mW) Max |
| Communication Interface | SPI (Standard 4-wire interface) |
| Receiving Sensitivity | -147dBm (at 0.3kbps air rate) |
| Reference Distance | 7000 meters (Clear and open environment) |
| Supply Voltage | 1.8V to 3.7V DC (3.3V recommended) |
| Dimensions | 10 × 10 × 2.5 mm; SMD Package |
| Data Buffer | 256 Byte FIFO for large capacity transmission |
| Certifications | CE, FCC, RoHS Compliant |
| Data Updated | May 2026 |

Interface & Pin Definition
Optimized Hardware Integration — Professional RF Design
The module uses a standard 1.27mm stamp hole interface for easy SMT production. It supports integrated RF switch control and provides configurable GPIOs for flexible software-defined functionality.
Ideal Applications
Smart locks, security sensors, lighting control, appliance telemetry
Wireless water, electricity, and gas meters (AMI) for utility management
Remote I/O systems, industrial sensors, factory automation links
Soil moisture monitoring, irrigation automation, greenhouse sensing
Pet tracking, luggage monitoring, supply chain data collection

Developer Resources
Comprehensive technical manuals, demo codes, and integration guides for E22 series modules.
📄 Download User Manual 🛒 Order Development KitsFrequently Asked Questions
Q: What is the difference between the E22 and E220 series?
A: The E22 series uses the Semtech SX1268/SX1262 chips, offering higher link budget and better interference immunity for mission-critical industrial tasks. The E220 series uses the LLCC68 chip, providing a more cost-effective solution for standard commercial IoT projects.
Q: How does the ultra-small volume affect heat dissipation?
A: Despite the 10x10mm size, our professional-grade LoRa modules are designed with high-efficiency RF paths and a multi-layer PCB for optimal thermal performance. At the maximum 22dBm output, heat is managed safely within industrial temperature limits.
Q: Can I customize the frequency band for global markets?
A: Yes. We offer variants covering global sub-GHz bands, including 433MHz/470MHz for Asian/industrial bands and 868MHz/915MHz for European and American ISM bands. Custom ODM services are also available for specific hardware requirements.
Q: What antenna interface does this module use?
A: The module supports both stamp hole and IPEX connector options. The stamp hole is ideal for compact internal antennas on your PCB, while the IPEX allows for external high-gain antennas to maximize transmission range.
Q: Is this module compatible with standard LoRaWAN gateways?
A: This is an SPI-based radio transceiver module. While it provides the physical layer for LoRa, you will need a LoRaWAN software stack (like Semtech's LoRaMAC-node) on your host MCU to connect to standard LoRaWAN gateways.